Biotechnology: New benefits, new questions

Clinical benefits of remote ischemic preconditioning: new insights...and new questions.

New Trends in Nucleoside Biotechnology

This review focuses on new trends in nucleoside biotechnology, which have emerged during the last decade. Continuously growing interest in the study of this class of compounds is fueled by a number of factors: ( i ) a growing need for large-scale production of natural 2 ' -deoxy- β -D-ribonucleosides as well as their analogs with modifications in the carbohydrate and base fragments, which can...

A New Branch of Biotechnology

Nucleoporins and Transcription: New Connections, New Questions

It seems to make perfect sense that RNA, which must be exported from the nucleus to be translated, would be produced near or in association with nuclear pores. Indeed, recent reports proposed that Saccharomyces cerevisiae genes located close to the nuclear pore complex (NPC) tend to be highly transcribed [1,2] and that, upon activation, some genes relocate from the nuclear interior to the nucle...

Primary Aldosteronism: New Answers, New Questions.

There have been 2, and possibly 3, major questions for primary aldosteronism (PA) answered at least in principle over the past 5 years. The first is that of somatic mutations underlying the majority of aldosterone producing adenomas. The second is the extension of our knowledge of the genetics of familial hypertension, and the third the role of renal intercalated cells in sodium homeostasis. Ne...